Central Laboratory
052 / 647 337

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150.00 BGN

General information:

Celiac disease is a disease of the digestive system in which the main damage is localized in the small intestine. Patients have an intolerance to a protein known as gluten, which is contained in wheat, rye, barley and many semi-finished products. When people with this disease consume them, their immune system triggers an autoimmune response that damages the lining of the small intestine. The result is a complete obliteration of the specific, microscopic, finger-like formations in the lumen of the small intestine, called small intestinal villi. Through them, the assimilation of all food ingredients takes place. This is why people with celiac disease develop the signs of severe malnutrition, regardless of the quantity and quality of the food they eat.

Celiac disease is also known as celiac sprue, non-tropical sprue, and in our country as gluten enteropathy. The disease is genetically determined, which means that it can also be found in other members of the patient's family. In some cases, it can be unlocked in its active form by surgical interventions, pregnancy, viral infections, stressful situations.

DNA analysis for gluten intolerance / Celiac Disease / with molecular genetic testing is performed at Laborexpress 2000.

The analysis includes: Determination of HLA-DQ2 and HLA-DQ8 haplotypes (13 mutations in total).

Sample required:

Venous blood with anticoagulant (EDTA)

Key words:

celiac disease, gluten intolerance

 

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