Insulin resistance panel

Blood glucose level

Lipids profile ( HDL,LDL,VLDL, triglycerids, cholesterol total)

Insulin

C-peptide

HOMA index

hsCRP

HOMA 2 

 Insulin resistance, identified as an impaired biologic response to insulin stimulation of target tissues, primarily involves liver, muscle, and adipose tissue. Insulin resistance impairs glucose disposal, resulting in a compensatory increase in beta-cell insulin production and hyperinsulinemia. The metabolic consequences of insulin resistance can result in hyperglycemia, hypertension, dyslipidemia, hyperuricemia, elevated inflammatory markers, endothelial dysfunction, and a prothrombotic state. The predominant consequence of insulin resistance is type 2 diabetes(T2D). Insulin resistance is thought to precede the development of T2D by 10 to 15 years. Lifestyle modifications should be the primary focus when treating insulin resistance. Nutritional intervention with calorie reduction and avoidance of carbohydrates that stimulate excessive insulin demand is a cornerstone of treatment. Physical activity helps to increase energy expenditure and improve skeletal muscle insulin sensitivity. Medications also can improve insulin response and reduce insulin demand. Most of the complications from insulin resistance are related to the development of vascular complications and nonalcoholic fatty liver disease. 

Samling

venous blood, fasting 12h, morning till 9:00