CBC 22 with differential, CRP, SAA

General Information:

This analysis includes:

• WBC (Leucocytes - count)
• Ly% (Lymphocytes)
• Mo% (Monocytes)
• MID% (Mo+Eo+Ba)
• Eos% (Eosinophils)
• Baso% (Basophils)
• Neu% (Neutrophils)
• Ly# (Lymphocytes)
• Mo# (Monocytes)
• MID# (Mo+Eo+Ba)
• Eos# (Eosinophils)
• Baso# (Basophils)
• Neu# (Neutrophils)
• RBC (Erythrocytes - count)
• Hgb (Hemoglobin)
• Hct (Hematocrit)
• MCV (Mean corpuscular volume)
• MCH (Mean corpuscular hemoglobin)
• MCHC (Mean corpuscular hemoglobin concentration)
• RDW (Red cell distribution width)
• Plt (Thrombocytes)
• MPV (Mean platelet volume)
• Pct (Plasmocytes)
• PDW (Platelet Distribution Width) SD
• PDW (Platelet Distribution Width) CV
• CRP is one of the strongest acute phase reactants whose concentration may increase to 1000 times after acute myocardial infarction, stress, trauma, infection, inflammation, surgery, or neoplastic processes. CRP is used to assess the activity of inflammatory diseases (rheumatoid arthritis); for detection of concomitant SLE, leukaemias, after surgery; renal transplant rejection; neonatal septicemia and meningitis, etc. It is important to note that CRP is a very dynamic indicator, it is possible to increase or decrease at times for several days.

• Serum Amyloid A (SAA) is an acute-phase protein, meaning it’s produced by the liver in response to inflammation, infection, or trauma. It plays an important role in the body's immune response.

   Inflammation marker: SAA levels rise very quickly—within 6 to 12 hours—after an inflammatory trigger. It can rise even faster and higher than CRP (C-reactive protein).

  • Diagnostic use: SAA helps detect and monitor infections, autoimmune diseases, and certain cancers. When combined with other tests like CRP and blood counts, it can help distinguish between bacterial, viral, or mixed infections.

  • Amyloidosis: In cases of chronic inflammation, excess SAA can deposit in tissues as amyloid fibers, leading to organ damage—a condition known as secondary amyloidosis.

Sample required:

Venous or capilar blood in the morning in fasting