Coagulation Factor 5 (Proaccelerin)

General information:

The factor enhances the process of converting prothrombin to thrombin, which is essential in the formation of a clot. Deficiency of this factor is a hereditary autosomal recessive, i. the two parents are carriers of the gene. Men and women are equally affected.

Symptoms of the deficiency are: bruising, subcutaneous bruising, bleeding from the nose, gums and oral cavity. Babies are at an increased risk of intracranial haemorrhage, in adults there are bleeding from the lungs, GIT, severe metrorrhagia in women.

The diagnosis is based on the values ​​of partial thromboplastin time (aPTT), prothrombin time (PT), clotting time (TCT), the present factor-specific study.
Inherited deficiencies are rare, occurring early and usually affect a coagulation factor.

Sample required:

Venous blood

Key words:

Factor V, Labile Factor, Proaccelerin