Clostridium difficile - GDH/Toxin A/B
General information:
A modern combined test for the detection of bacterial toxins A/B as well as the enzyme glutamate dehydrogenase (GDH). The result comes out within the day.
Infections with the microorganism affect adults and children. Clostridium difficile is widely distributed in the external environment, it is also found as a normal inhabitant of the intestine, especially at a younger age. The mechanism of transmission of the infection is fecal-oral, through contaminated food products, surfaces, infected hands, etc.
In principle, it can be a normal/harmless/inhabitant of the large intestine in 5-15%, but under certain conditions symptoms can develop. Most often they are expressed in:
- Diarrheal syndrome indistinguishable from other intestinal causes
- Inflammation of the colon/colitis/with abdominal pain, bloating and fatigue
- Pseudomembranous colitis - the most severe form, characterized by toxic infection syndrome, bloody-mucous diarrhea, rapid development of dehydration, hypovolemia, demineralization, acidosis and hypoproteinemia.
Risk factors and groups for Clostridium difficile infection are:
- Recently visited hospital facilities
- After taking antibiotics associated with the disease - clindamycin, aminopenicillins, cephalosporins and fluoroquinolones
- Patients with reduced immunity and chronic diseases
- Pregnancy
- Patients taking antacids and after abdominal operations
- Patients diagnosed with irritable bowel syndrome
Sample required:
Faeces in sterile container