Liver Function – Diagnostic Panel

Professional assessment of key indicators for liver health

The “Liver Function” diagnostic panel includes essential biochemical tests that provide comprehensive information about the condition of the liver, bile ducts and the synthetic function of the body. It is suitable both for preventive screening and in cases of suspected liver damage, viral hepatitis, toxic exposure, metabolic disorders or biliary obstruction.

The sample is collected from venous blood, and results are available within the same day.

Included tests and their significance

ASAT (Aspartate Aminotransferase)

ASAT is an enzyme found in the liver, cardiac muscle and skeletal muscles. Elevated levels may indicate:

• liver cell damage;

• cardiac conditions;

• muscle injury or intense physical activity.

The ASAT/ALAT ratio helps differentiate between various types of liver and non‑liver damage.

ALAT (Alanine Aminotransferase)

ALAT is the most specific enzyme for assessing liver injury. Elevated levels are observed in:

• viral hepatitis;

• fatty liver disease (steatosis);

• toxic liver damage caused by medications or alcohol;

• inflammatory liver conditions.

ALAT is a sensitive marker for early changes in liver function.

GGT (Gamma‑Glutamyl Transferase)

GGT is an enzyme associated with the function of the bile ducts. Elevated levels may indicate:

• bile flow obstruction (cholestasis);

• alcohol‑related liver damage;

• use of medications that affect the liver.

The combination GGT + Alkaline Phosphatase is characteristic of biliary tract disorders.

Bilirubin (total and direct)

Bilirubin is a product of hemoglobin breakdown.

• Total bilirubin reflects the overall amount in the blood.

• Direct bilirubin represents the portion processed by the liver.

Elevated levels may indicate:

• hepatitis or cirrhosis;

• obstruction of the bile ducts;

• increased breakdown of red blood cells (hemolysis).

Clinically, this may present as jaundice, dark urine and pale stools.

Total Protein

The liver synthesizes most of the proteins found in the blood. Low levels may indicate:

• impaired synthetic liver function in severe liver disease;

• malnutrition or chronic inflammatory conditions.

High levels may occur in dehydration or certain inflammatory states.

Alkaline Phosphatase (ALP)

ALP is an enzyme that increases in cases of:

• bile duct obstruction;

• bone disorders.

The combination ALP + GGT helps determine whether the origin is hepatic or biliary.

Lactate Dehydrogenase (LDH)

LDH is a nonspecific marker of cellular damage. Elevated levels may be seen in:

• liver diseases;

• anemia;

• cardiac or pulmonary conditions.

LDH complements the overall assessment of tissue health.

Fibrinogen

Fibrinogen is a protein synthesized in the liver and is essential for blood clotting. Low levels may indicate:

• severe liver impairment;

• coagulation disorders;

• increased risk of bleeding.

High levels may occur in:

• acute inflammatory processes;

• infections;

• stress‑related physiological responses.

Fibrinogen is an important marker of the liver’s synthetic capacity and the body’s overall condition.

Who is the “Liver Function” panel suitable for?

This diagnostic panel is recommended for individuals with:

• pain or heaviness in the right upper abdomen;

• fatigue or general weakness;

• use of medications that affect the liver;

• alcohol consumption;

• overweight or metabolic syndrome;

• suspected viral hepatitis;

• routine preventive screening.

Advantages of the panel

• Fast and reliable laboratory testing

• Comprehensive evaluation of liver function

• Early detection of liver damage

• Suitable for treatment monitoring

• Same‑day results